Staff:
Angelo Cagnacci, Full Professor
Sergio Costantini, Associate Professor
Simone Ferrero, Associate Professor
Franco Gorlero, Associate Professor
Ambrogio Pietro Londero, Associate Professor
Claudia Massarotti, Fixed-term Researcher
Lines of research include:
- Early diagnosis of gynecologic cancers, particularly endometrial and ovarian cancer. Through the application of innovative radiomics and artificial intelligence techniques to ultrasound images, the various types of ovarian cancer and endometrial changes will be defined to have a pre-surgical diagnosis of the type of cancer present.
- Application of radiomics and artificial intelligence to the diagnosis of endometrial infertility that is associated with embryo implantation defects. Assessing the accuracy of this type of approach in defining a priori the possibility of embryo implantation.
- Analysis of endometrial microbiota in women with implantation defects and in women with conditions such as adenomyosis and endometriosis characterized by intense menstrual pain and profuse bleeding.
- Prevention Diagnosis and treatment of chronic pelvic pain and its most associated diseases such as adenomyosis and endometriosis. Research is developed in the study and identification of ultrasound signs of the female genital system that may lead to the appearance of pathologies such as adenomyosis and endometriosis, through tissue elastography and radiomic techniques, and in defining their pathogenetic mechanisms and the most innovative therapeutic interventions.
- Evaluation of the association between gastroenteric disorders and chronic pelvic pain pictures. Associations with gastroenteric disorders and alterations in the vaginal and intestinal microbiota are also explored in this area.
- Evaluation of the impact exerted by endocrine therapies on cardiovascular risk factors, such as metabolic alterations and changes in 24-hour blood pressure.
-Study of iatrogenic menopause, in general after gynecological and oncological pathology. The research is developed on the study of the peculiarities of menopausal symptoms of women survivors of cancer, characterizing the diversity in the field of the central nervous system, by means of assessment tests but also functional MRI, in the cardiovascular field, on various risk factors, and in the genito-urinary field on urinary, vaginal and sexuality disorders. Research is also based on assessment of changes in sense organ activity.
- Use and comparison between the effectiveness of treatments, even innovative, that can improve the quality of life of these women.
- Ultrasound studies in the study of pelvic floor defects with genital organ prolapse.
- Comparison of minimally invasive techniques in the treatment of pelvic floor defects.
- In vitro and in vivo research for the optimization of fertility preservation techniques in cancer patients.
- In vitro evaluation of natural killer cell activity present in circulating, peritoneal fluid, and tumor tissues of women with metastatic ovarian cancer.
- Searching for environmental factors that may influence the occurrence of pregnancy disorders such as pre-eclampsia and preterm delivery.
-Research of uterine factors that indicate the onset of labor in physiologic delivery and preterm delivery.
Third Mission activities:
The results of our studies and targeted educational meetings are made accessible through webinars and congresses organized for Obstetrics and Gynecology Specialists, Midwives and Related Subjects Specialists. Through scientific societies, small videos for women are produced and placed on the WEB